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Side effects are usually mild and improve as your body adjusts
The MHRA advises that insulin doses should not be reduced rapidly when initiating a GLP-1 receptor agonist, as this may increase the risk of diabetic ketoacidosis (DKA)
One study showed that depleted glutathione could then lead to depleted methionine
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This indicates the need for close monitoring when GLP-1 RAs and a dual GLP-1/GIP RA are co-administered, especially when starting treatment or increasing the dose
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