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The main clinical differential diagnosis in childhood is bruising caused by child abuse, potentially distinguishing features of which include lesions located in areas not exposed to accidental trauma (e.g., backs of the legs or abdomen), peculiar morphology (e.g., imprints caused by fingers, the dental arch, belts, etc.), and the time course of lesion appearance.4,5 In rarer cases extensive bruising may constitute the initial manifestation of coagulopathies that can be detected by laboratory analyses

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However, the metabolic changes that occur can feel significant, particularly the return of appetite and potential weight regain

It acts on the brain, especially in an area called the hypothalamus which controls hunger and fullness, to reduce hunger and food cravings, making one feel full sooner