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Conversely, stages of a womans life, such as adolescence, perimenopause and menopause, that are associated with reduced estradiol, are also associated with weight gain
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She warned: More research is needed on their long-term impact, how these drugs affect cancer risk, and how best to support people to maintain a healthy weight
The compound has been studied in trials lasting up to 68 weeks, which provides useful medium-term data but leaves questions about effects beyond 2 years of continuous use
Trial protocols typically start at 2 mg once weekly with monthly titration up to 12 mg
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