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From a pharmacological standpoint, several considerations are relevant: Gastrointestinal effects : Retatrutide, like other GLP-1-based therapies, commonly causes nausea, vomiting, diarrhoea, and reduced appetite
Choice of control (Control) A pure 2-arm, placebo-controlled, RCT between a single drug and placebo may not be acceptable for prospective participants to be randomised into, given documented multi-systemic benefits of GLP-1 administration
Biochem Biophys Res Commun 2008
Side Effects and Precautions Common Side Effects Common side effects of semaglutide injection include nausea, vomiting, diarrhea, and constipation
What I find really interesting and unexpected is that our patients didnt have significant weight loss, and the BMI Z-score and percentile were stable, Panganiban said
