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In the process of oxidative phosphorylation, complex I (NADH quinone oxidoreductase) acts as the entry point for electrons from the mitochondrial matrix into the electron transport chain (ETC) by catalyzing the electron transfer from NADH into the ETC subunits 22

Outcome measures cover histological damage scoring, cytokine panels (TNF-, IL-6, IL-10), mucosal blood flow, tight junction protein expression by Western blot, and stool consistency scoring for colitis models

No complications are typically associated with these lesions

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