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Notably, RSL3 is widely used as a pharmacological inhibitor of GPX4, although studies in cell-free systems suggest that it may also exhibit inhibitory activity toward thioredoxin reductase 1 (TXNRD1), a key NADPH-dependent antioxidant enzyme that maintains thioredoxin-mediated redox homeostasis

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Mild side effects may occur, such as a slight redness at the injection site, although these usually go away within a few hours after the injection

Foods that are high in vitamin B12 include