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The standard Wegovy escalation The FDA-approved schedule for semaglutide (Wegovy) for chronic weight management follows five steps: Weeks 1 to 4: 0.25 mg once weekly Weeks 5 to 8: 0.5 mg once weekly Weeks 9 to 12: 1.0 mg once weekly Weeks 13 to 16: 1.7 mg once weekly Week 17 onward: 2.4 mg once weekly (maintenance) Each step lasts a minimum of four weeks
d The Z statistic of the Mann-Whitney U test
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