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Peptides are not illegal to use or own, but as the BBC notes, "they are not approved for human use, so are not subject to the quality controls that govern pharmaceutical manufacturing." In 2023, under the Biden administration, the FDA classified a group of over a dozen peptides as Category 2 substances, which may "present significant safety risks," effectively banning their use
Conversely, patients who carry variants in hydroxysteroid 17-beta dehydrogenase 13 (HSD17B13, rs72613567) and mitochondrial amidoxime-reducing component 1 (MARC1, rs2642438) are more protected than the general population (48, 49)
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