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a Synergy 2 (BioTek)
The trade-off is pharmacokinetic: oral delivery subjects the peptide to stomach acid (pH roughly 1.5-2.0 fasting) and proteolytic enzymes including pepsin and pancreatic proteases before any absorption can occur
Probasco JC, Felling RJ, Carson JT, Dorsey ER, Niessen TM
While the smaller size of the test sets (particularly "External 2" and DLS-100) makes meaningful comparisons hard, there appear to be minimal differences between the different model architectures
One is a dual agonist
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