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IGF-1 is primarily synthesized in the liver, and then binds to specific receptors of cellular structures inside the bodymost notably, in bones, muscle, and cartilage

68,69 Despite its critical involvement in methylation reactions, the precise mechanisms by which SAM dysregulation contributes to diseases such as cancer, neurodegenerative disorders, and liver diseases are still not fully elucidated

A self-assembled nanocarrier loading teniposide improves the oral delivery and drug concentration in tumor

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