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Originally engineered at Washington State University by the Harding lab and later licensed to M3 Biotechnology, Dihexa retains the angiotensin IV pharmacophore for AT4 receptor binding while incorporating N-hexanoyl and aminohexanoic acid modifications that confer metabolic stability and lipophilic BBB penetration
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Regular monitoring and follow-up with prescribing healthcare providers is essential for appropriate management of each individual patient
Gupta AK, Venkataraman M, Talukder M, Bamimore MA
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