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What they found (summary): MC1R: melanogenesis, pigmentation, anti-inflammation MC2R: ACTH receptor in the adrenals (Melanotan II does not act) MC3R: energy, cardiovascular function, anti-inflammation MC4R: appetite (central control), sexual function, autonomic regulation MC5R: exocrine glands (sebaceous, lacrimal, salivary) Mutations in MC4R are the most common monogenic cause of obesity in humans Why it matters: Cones review article is the reference article for all of melanocortin pharmacology
It also enhances skin health, boosts immune function, and supports detoxification
Tell your healthcare provider if you have any side effect that bothers you or that does not go away
J., Scott, C
Unlike some GLP-1 side effects that may resolve when you stop the medication, dental damage can be permanent if left untreated
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