If your goal is, I want to take the weight off and just keep the weight off, you're missing the point of improving health." That means becoming the person who is active, who takes up a sport, who's careful about what's in the house, who has reasons to stay motivated beyond a number on the scale
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A subsequent 2024 analysis published in JAMA Network Open by the same group expanded the lens, examining GLP-1 receptor agonists vs insulin and metformin across 13 obesity-associated cancers in more than 1.6 million patients with type 2 diabetes
A larger percentage of liver cancers in these cases occur before end-stage liver failure, and thus are less likely to be screened for, increasing the tendencies for liver tumors to be larger and more difficult to treat at the time they are diagnosed
This is the time to begin ovulation tracking if desired (using ovulation predictor kits or basal body temperature), optimize timing for conception attempts, ensure your weight is stable (not rapidly changing up or down), and confirm with your doctor that youre ready to begin trying
