[1] [2] Symptoms that have been described include: Injection site reactions : redness, swelling, itching, or mild bruising at the site of subcutaneous administration consistent with class effects seen with semaglutide and tirzepatide (see eMC SmPCs for Wegovy, Ozempic, and Mounjaro for comparator data) Pruritus or urticaria : patchy or widespread skin itching or redness, which may reflect a hypersensitivity response again consistent with known class effects of GLP-1-based therapies [17] Generalised skin sensitivity : heightened sensitivity to touch, temperature, or pressure beyond the injection site
Likewise, clinical trials evaluating antiviral or anti-inflammatory endpoints, such as viral load, disease outcomes, and cytokine biomarkers, are either preliminary or lacking and warrant further investigation
These data come from Cosmos, a dataset created in collaboration with a community of Epic health systems representing more than 277 million patient records from 1,500 hospitals and more than 36,000 clinics from all 50 states, Lebanon, and Saudi Arabia
In contrast, commercial patches typically contain herbal ingredients, such as berberine, which have minimal evidence for weight loss, especially when applied to the skin