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C.GildenJ
Hickson, L
Common methods include radiolabeling (attaching a detectable isotope to the compound and tracking its distribution via imaging), microdialysis (sampling interstitial fluid directly from brain tissue), and post-mortem tissue analysis measuring compound concentrations in specific brain regions
Quantification of inflammatory and degradation marker Total mouse PGE 2 , IL-6, MMP-3, and MMP-13 concentration of primary murine chondrocytes (p0) or murine macrophage cell line (p + 9) after 24 h of treatment was assayed in cell-free supernatants using an ELISA kit, according to the manufacturers instructions
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