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doi: 10.5049/EBP.2013.11.2.41 25 IchiharaASuzukiFNakagawaTKaneshiroYTakemitsuTSakodaMet al
It is used in medically supervised weight loss programs for eligible patients and may support: Appetite control Reduced calorie intake Improved metabolic response Tirzepatide is prescribed only when medically appropriate following a consultation and evaluation
The trial demonstrated a significant reduction of 25% in the primary composite outcome of cardiovascular death and first HFH (19.4% versus 24.7% [HR 0.75
LC is a substrate for gut microbiota, and its metabolism affects both microbial composition and human metabolic pathways
Additionally, MEP modulated the gut microbiota by decreasing harmful taxa such as Acinetobacter and increasing Firmicutes, Lactobacillus , which are important for the hypolipidemic effect, and Prevotella , which is related to glucose metabolism (160)
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