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Studies were selected based on their relevance to the interactions between GLP-1 receptor agonists and the gut microbiota, with particular attention to mechanisms potentially influencing treatment response and metabolic outcomes

In the few individuals who did have preexisting cross-reactive antibodies, these often targeted the S2 region of spike that is more conserved across coronaviruses but that predominantly induces nonneutralizing antibodies [72, 73]

Some researchers have explored their combined use in laboratory settings, though the majority of published literature examines each compound independently

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