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Results Combined treatment of l-carnitine and metformin significantly decreased the blood glucose level of diabetic rats at day 14 and significantly decreased the plasma nitrite level and plasma MDA level of diabetic rats as compared to metformin-alone and l-carnitine-alone-treated diabetic rats
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In the Pancreas: GLP-1 stimulates insulin secretion in a blood glucose dependentmanner hence decreasing B cell over function, enhancing Beta-cell survival rate, decreasing B- cell apoptosis and preserving B-Cell mass
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