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However, there were no significant differences between two groups ( P = 0.69)

Its regulation is also different from that of NRF2, which is mainly regulated by N-glycosylase 1 (NGLY1) and DNA loss inducer 1 homolog 2 (DDI2) [13, 14]

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Participants were randomly assigned to receive either semaglutide, a glucagon-like peptide-1 (GLP-1) receptor agonist, or a placebo, alongside lifestyle counseling for diet and physical activity