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Patients taking GLP-1 agonists most commonly complain of gastrointestinal effects, 2 such as unsettled stomach, upset GI tract, variable bowel movements or trouble with elimination, abdominal discomfort, and gastroesophageal discomfort
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Non-alcoholic steatohepatitis (NASH) is relevant given GLP-1 agonists show hepatic benefits and weight loss ameliorates NASH
Standard escalation approach The typical retatrutide dose escalation starts low and increases over several weeks
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