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The combination of GLP-1R agonists with each other has not been studied previously, suggesting that due to their similar mode of action, there would not be an enhancement in therapy from this combination

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The nitric oxide pathway contributes by relaxing vascular smooth muscle and creating conditions permissive for new vessel sprouting

Compared to those with LE-specific lesions, those with nonspecific lesions tend to have increased SLE disease activity

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