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Off-label use at lower doses (such as 1 mg daily) is explored in wellness contexts but lacks equivalent RCT support at those doses

Diabetologia 65(Suppl 1):S290S291 Gastaldelli A, Cusi K, Fernandez Lando L, Bray R, Brouwers B, Rodriguez A (2022) Effect of tirzepatide versus insulin degludec on liver fat content and abdominal adipose tissue in people with type 2 diabetes (SURPASS-3 MRI): a substudy of the randomised, open-label, parallel-group, phase 3 SURPASS-3 trial

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This appetite suppression effect naturally reduces the amount of food you eat

Multi-pathway metabolic signaling