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Compared with VDAC blockade, USP30 inhibition benefits from enzymatic tractability and measurable pharmacodynamic readouts, although its efficacy is still likely to depend on residual integrity of PINK1/Parkin-associated quality control pathways in the target cells

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There were no reports of interactions between Ozempic and antidepressant medications, amitriptyline

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S.DostertC.NonnenmacherY.CoxM.et al (2017)