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Short-term studies havent found acute safety issues, but because there are no long-term human studies, its safety over time is unknown

PLoS ONE 6:e16957 Ramsay RR, Gandour RD, van der Leij FR (2001) Molecular enzymology of carnitine transfer and transport

Chronic acetyl-l-carnitine alters brain energy metabolism and increases noradrenaline and serotonin content in healthy mice

Comparative analysis of detoxification enzymes in Acyrthosiphon pisum and Myzus persicae

GHK-Cu works through copper delivery to metalloenzymes and broad gene expression modulation, affecting not only collagen synthesis but also collagen cross-linking (via lysyl oxidase), glycosaminoglycan production, anti-inflammatory pathways, and antioxidant defense systems