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Tirzepatide population pharmacokinetics and exposure Schneck 19-study pooled popPK (CL/F 0.061 L/h, half-life 5.4 d, accumulation 1.7x, body-weight covariate +22% at 70 kg / -33% at 120 kg)

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Tirzepatide's adverse effect profile is well-characterized from extensive clinical trial data

So, its a little bit more of the Wild West, said Spittler, who is also an associate professor at the University of Colorado Anschutz School of Medicine

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