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Biochim Biophys Acta Mol Basis Dis 1871(7):167955 Divoux A, Erdos E, Whytock K et al (2022) Transcriptional and DNA Methylation signatures of subcutaneous adipose tissue and adipose-derived stem cells in PCOS women
Following GLP-1 RA discontinuation, the patient experienced an increase in appetite, regained 7 kg (weight 167 kg, 79.4 kg/m 2 ) and was also later diagnosed with type 2 diabetes
"It was impressive to see that every dose of retatrutide resulted in clinically meaningful weight reduction for nearly all participants, and people with severe obesity on the highest dose lost on average 30% of their body weight over two years
