Drugs that treat other Alzheimers risk factors, like herpes virus infection or high cholesterol, dont seem to benefit people with the disease in well-controlled clinical trials
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In addition, the-KG can be converted to succinyl-CoA, which is also an activator of GDH [16]
Collectively, while ferroptosis plays a significant role in the pathogenesis of both TMJ OA and KOA, the specific effects may differ due to the distinct tissue characteristics, mechanical stress, and inflammatory environments of TMJ and knee
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