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Now this post-Ozempic reality poses a particular existential crisis for the for-profit weight-loss companies that have made billions of dollars, for decades, by telling their customers to have more willpower

The class effect: GLP-1 drugs and male reproductive markers Several published studies of approved GLP-1 medications in men with obesity-related hypogonadism have reported reproductive findings: A randomized trial of liraglutide in men with obesity and functional hypogonadism reported increases in total testosterone of approximately 1.5-2 nmol/L over 16 weeks alongside 5-7 kg weight loss (Jensterle et al.)

Humira continued to be the costliest prescription drug for self-funded health plans in 2023 by a comfortable margin, according to a recent Milliman commercial drug trends review

Wegovy EPAR product information (PDF)

I know that was a lot