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Following the successes of GLP-1 RAs, manufacturers have worked to produce similar outcomes with newer agents that affect the incretin pathways including not only GLP1 receptors but also GIP and glucagon receptors
The NIH factsheet explains that no tolerable upper intake level has been set for B12, because it has a low potential for toxicity in healthy people
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A pesquisa mais recente aponta que os agonistas de GLP-1 podem ter benefcio em: Doenas cardiovasculares (infarto, insuficincia cardaca) Alzheimer, Parkinson e outras doenas neurolgicas Apneia obstrutiva do sono Esteatose heptica e NASH (doena gordurosa do fgado) Artrite e osteoartrite Reduo de inflamao crnica Transtornos alimentares e uso de substncias (vcios) Isso acontece porque o GLP-1 atua em mltimos rgos do corpo , e seus efeitos vo alm da glicose e do apetite
Between 15-40% of people over 60 have low serum B12 levels (Pacholok & Stuart, 2011)
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