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With Novo Nordisk joining a distinguished speaker faculty that already included industry giants like Eli Lilly, AstraZeneca, and Merck , the summit served as the global engine for de-risking high-investment multi-target therapeutics through advanced pharmacometric modeling and adaptive trial designs

For most adults, the first-line approach involves lifestyle modification , including a balanced, calorie-controlled diet and increased physical activity

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The SURPASS-CVOT trial, where dulaglutide at the dose of 1.5 mg/week or at the highest tolerated dose, is the comparator, has a distinctive design from the other trials: the primary endpoint is the time to the first manifestation of any major adverse CV event (MACE), defined as myocardial infarction, stroke or CV death