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The CSF-to-plasma ratio is approximately 0.4%, confirming that a small but definite amount of the drug penetrates the central nervous system (CNS) (Scheltens et al., 2026)
J Clin Gastroenterol 2010
It can also lighten skin tone by converting melanin to a lighter colour and then deactivating the enzyme tyrosinase, which helps produce the pigment
Natural product andrographolide alleviated APAP-induced liver fibrosis by activating Nrf2 antioxidant pathway
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