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doi: 10.1093/ajcn/52.6.1087 66 WeichenbergerCXRiveraMTVanderpasJ

When glutathione synthesis or recycling is compromised, hydrogen peroxide and lipid peroxides accumulate, oxidizing endothelial membranes and proteins (6)

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Unlike the current paradigm, mutations of the GNAS1 gene reduce TSHR signaling and, by either inhibiting cAMP production or increasing the Gns activity (lack of regulation), slow down the proliferation