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Interventions We modelled four interventions: increase in use of SGLT2is or GLP-1 RAs to 75% of the total population with type 2 diabetes, and increase in use of SGLT2is or GLP-1 RAs to 75% of the secondary prevention population
The broader secretagogue field offers a sobering precedent: the orally active GHS ibutamoren (MK-677) durably raised IGF-1 in trials, yet did not reliably convert that biochemical change into the functional benefits investigators hoped for
Over the past ten years, GLP-1 receptor agonists (GLP-1RAs) such as Ozempic, Wegovy, and Mounjaro have taken the pharmaceutical world by storm
In the context of diabetes, biomimetic hydrogel depot technology has been utilized for the sustained delivery of GLP-1 receptor agonists
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