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The primary outcome assessed in this study was the average HbA1c levels

Animal data shows favorable nutrient partitioning, but direct fat-mobilizing effects are minimal compared to growth hormone itself (Yoshida & Delafontaine, 2020)

Conditioned media was collected from the PC cultures in the second day after the seedings and mixed in a 1:1 ratio with the medium of hEC [24]

Based on available Phase 2 data, retatrutide appears to offer a promising benefit profile, particularly in terms of the magnitude of weight loss and its potential to address multiple metabolic pathways simultaneously

We therefore investigated the predictive value of these variables in our cohort, after adjusting for the non-genetic factors described above (Supplementary Information)