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What actually determines success is whether you inject at the same time every week without letting schedule conflicts push you into a rotating dosing pattern
There are some data to suggest that insulin resistance also occurs in PD [70], however, this is controversial since systemic insulin resistance is not present in de novo, medication-free PD patients [71], and brain insulin resistance is not present in cognitively normal PD cases [72]
Most users take half the daily dose upon waking and the remaining half in the afternoon or early evening
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