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We believe that a greater understanding of how steroids modulate neural network activity will help lay the foundation for a unifying theory of neurosteroid action in the brain centered on a systems level pharmacological connectome. Synthesis, Structure, Transport and Cellular Targets of Neurosteroids Synthesis and Translocation Neurosteroid synthesis involves translocation of cholesterol across the mitochondrial membrane by transport proteins, such as the steroidogenic acute regulatory protein (StAR protein), the translocator protein (TSPO), voltage-dependent anion channel (VDAC) protein and the adenine nucleotide transporter (ANT) protein (8689)

Heller, F

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Because osteoarthritis involves cartilage breakdown and joint wear, peptides associated with tissue repair and collagen support are often the main focus