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In women with PCOS who have vitamin D deficiencies, co-supplementation of calcium and vitamin D has demonstrated improvements in -cell function, TAC, high-sensitivity C-reactive protein (hs-CRP), and glutathione (GSH) levels [142]

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Tirzepatide with B12 is popular because GLP-1 medications can sometimes reduce absorption of certain vitamins, and B12 deficiency is associated with fatigue, a side effect some tirzepatide users report

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