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First, we observed no cell lysis nor toxicity using NCI H716, GLUTag, and human intestinal enteroids when incubated with Hld Se under the conditions tested

mPTP opening is detrimental to mitochondria, resulting in the disintegration of their membrane structure, increased ROS concentrations, and depolarization of mitochondrial membrane potential (Grlach et al

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The increase in heart rate is also of importance in patients with heart failure (HF)

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