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Structural characterization and hypoglycemic effect via stimulating glucagon-like peptide-1 secretion of two polysaccharides from Dendrobium officinale
Cellular uptake was evaluated in SH-SY5Y neuroblastoma and hBMECs using confocal laser scanning microscopy and flow cytometry revealing 5.4X higher uptake of lactoferrin-conjugated nanoparticles as compared to non-conjugated PLGA NPs following 5 h of exposure
As shown in Figure 4A, cinchonine potentiated insulin secretion under high glucose conditions (11.1 and 16.7 mM) but had no effect under 2.8 mM glucose, which suggested that cinchonine induced insulin release in a glucose-dependent manner
Your body produces many peptides naturally, but their levels decline with age
It binds the same pituitary receptor that the bodys own GHRH targets, telling the pituitary gland to release growth hormone in the same way it would naturally
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