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Much of the evidence comes from animal studies, cell studies, or early clinical research
Vitamin B12 does require the initial loading dose period, especially in very deficient cats, so improvements will not be immediate
This characteristic suggests the peptide works through regulatory mechanisms that plateau rather than dose-dependent stimulation that could run out of control
Zheng et al., 2020)
A 2019 case report describes a case of a young woman who was treated for severe pernicious anemia with multiple daily doses of 1 milligram (mg) of cyanocobalamin, a synthetic form of B12
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