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Son SM, Shin H-J, Byun J, Kook SY, Moon M, Chang YJ, et al
Research has explored its influence on growth hormone signaling pathways, with interest in its receptor specificity and minimal activity at other endocrine receptors when examined under controlled laboratory conditions
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Electrophysiological recordings further supported this, revealing that Dihexa caused a 1.6-fold increase and Nle-AngIV caused a 1.7-fold increase in the frequency of AMPA-mediated mEPSCs compared to vehicle-treated neurons, indicating an expansion of functional synapses without altering individual synapse properties such as amplitude, rise, or decay times
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