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This is consistent with recent findings by Vuralli et al
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GLP-1 has been reported to promote the production of anti-inflammatory cytokines in various organs including the adipose tissue and pancreas, and the brain (Dobrian et al., 2011
Howard says: Sweating and cooling both depend on having enough fluid on board, so someone who has quietly become depleted has far less reserve to draw on once the temperature rises. Together, fluid loss and insufficient cooling can lead to heat exhaustion and other heat-related illnesses
The study also points to what patients may need beyond the prescription itself: clearer counseling about side effects, steadier clinical support, behavioral strategies, peer connection, and policies that make access less dependent on wealth, luck, or sheer persistence
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