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We chose 2018 as the starting year because the most recent approved GLP-1 RA (semaglutide) except for tirzepatide was marketed in 2017, and the ending date was set as the most recent quarter when data were available
It is present in every cell, but the liver contains the highest concentrations up to 5-10 mM
Maintain vigilance year-round rather than only during extreme seasons
Notably, no cases of clinically significant hypoglycemia, medullary thyroid cancer, or C-cell hyperplasia were reported in published trial data
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