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Access Issues : Over 54% of users struggle to afford the medication, with 47.6% stopping treatment within the first year

Women account for 22% of those who have ever used GLP-1s in 2025, compared with 14% of men

PubMed laboratory research record [PMID: 35740321] PubMed record related to this compound for laboratory literature review

On the other hand, Mounjaro delivers even greater metabolic benefits, with studies showing up to 20% weight loss, making it a formidable contender for both diabetes and obesity treatment

Adaptation to the medications, requiring higher and higher doses to maintain the same satiety effects Individual biologic differences, leading to different effects of GLP medications than the norm