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Following the 6-wk feeding period, average daily intake (calories) by WT and KO mice was no different (Table 1)

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1130Altimmune-1GLP-1R/GCGRpemvidutide48IIMOMENTUM482.4mg15.6%Altimmune34% PemvidutideGLP-1R/GCGRGLP-1PemvidutideEuPort pemvidutide IIMOMENTUM3911:1:1pemvidutide 1.2mg1.8mg2.4mg14850BMI37kg/m2104kg75% 481.2mg1.8mg2.4mg pemvidutide10.3%11.2%15.6%2.2%2.4mg50%15%30%20% pemvidutideHbA1c pemvidutide74.1%61.9%16.2%1.2mg1.8mg2.4mg pemvidutide5.1%19.2%19.6%

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