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For those on other medications, particularly insulin or high blood pressure pills, additional caution is required
However, in a phase II evaluation of the compound in hepatocellular carcinoma, no objective response was shown (Wu et al., 2010)
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Adjudicated MACE-4 events occurred in 109 participants and were not increased on tirzepatide compared with glargine (HR 074, 95% CI 051108)
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