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H.DuschaA.et al (2018)

This should be used in conjunction with other known methods of combating fatigue, such as losing weight, reducing stress, drinking less alcohol, and trying to partake in more physical activities

Sex, age, and comorbidity should not be treated as nuisance variables

Case presentation SL was a 44 year old Caucasian male with a past medical history of severe morbid obesity (BMI 99), heart failure with preserved ejection fraction, oxygen-dependent obesity hypoventilation syndrome (OHS), chronic non-healing leg wounds, anemia, uncontrolled hypertension on 2 anti-hypertensive agents, limited mobility, and major depressive disorder who presented to an academic medical center for treatment of acute on chronic diastolic heart failure due to progressive dyspnea

The following steps reflect general best practice for subcutaneous self-injection, consistent with Royal College of Nursing (RCN) guidance and NHS patient-facing advice for similar injectable medicines