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Anti wrinkle injections are not appropriate during pregnancy or breastfeeding, in patients with neuromuscular conditions (myasthenia gravis, Lambert-Eaton syndrome, motor neurone disease), patients on aminoglycoside antibiotics, those with active infection at the injection site, or those with known hypersensitivity to botulinum toxin

The proof-of-concept analysis focused on a subset of participants aged 1235 years who achieved at least 10% body weight loss during treatment

doi:10.1039/C5CS00165J

Adverse events were defined as any major reduction of oxygen saturation (e.g., requiring reversal medications or unexpected endotracheal intubation), or any other immediate complication (e.g., bleeding, perforation, seizures, or other reasons that required admission of the patient to the hospital following the EGD), as this is standard of clinical care at our institution

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