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Obviously, a few cases do not yet make an indication, but they certainly suggest that this hypothesis may well be worthy of further study

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(2014) published foundational work demonstrating that NNMT expression in adipose tissue correlates with metabolic parameters in preclinical models

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However, these effects, observed at a very early disease stage, probably by affecting autoimmunity, may not be so prominent and of substantial advantage in the advanced stages of GD when symptoms are present and first-line therapy might be applicable

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In conclusion, our study identifies astrocytic GABA dysregulation as a central mechanism in PTSD pathophysiology and demonstrates that targeting MAOB inhibition restores inhibitory balance and alleviates symptoms

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