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There are several experimental models available for studying the mechanisms of acute and chronic epilepsy (Rubio et al., 2010)

Recent animal- and human-based studies described the enhanced percentage of eryptotic erythrocytes in patients with hepatic failure and hyperbilirubinemia [210, 250, 280, 283, 284]

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The side-chain guanidyl group of Arg454 interacts with the carboxylate moiety of glycine to orient the substrate for attack on the acyl-phosphate intermediate (Herrera et al., 2007)